A systematic review and meta-analysis of global and social functioning among people at risk of bipolar disorder

M Watson; K Filia; A Stevens; S Cotton; B Nelson; A Ratheesh

Journal article

A systematic review and meta-analysis of global and social functioning among people at risk of bipolar disorder

M Watson, K Filia, A Stevens, S Cotton, B Nelson, A Ratheesh

Journal of Affective Disorders | Published : 2023

DOI: 10.1016/j.jad.2022.10.019

Abstract

Background: Functional status could predict development of bipolar disorder (BD) or have clinical significance. The relationship between BD risk and functioning is poorly understood. We undertook a systematic review examining the global and social functioning of those at risk for BD. Methods: We examined observational studies comparing a risk sample with healthy controls or full-threshold BD participants, using measures of global or social functioning. Risk status included family history of BD, meeting risk criteria, or having prodromal symptomatology, or premorbid functioning of persons with BD. Medline, PsycINFO, and Embase were searched. The Newcastle-Ottawa Scale for Cross-Sectional Stud..

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University of Melbourne Researchers

Kate Filia Author

Susan Cotton Author

Barnaby Nelson Author

Aswin Ratheesh Author

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Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

Funding KF was supported by a University of Melbourne Momentum Fellowship. SC was supported by an NHMRC Senior Research Fellowship (APP1136344) . BN was supported by an NHMRC Senior Research Fellowship (1137687) and a University of Melbourne Dame Kate Campbell Fellowship. AR was supported by an NHMRC Early Career Fellowship (GNT1160108) .